Medicine

MTBBench

MTBBench evaluates multimodal LLMs on sequential clinical decision-making in oncology. Two cohorts: HANCOCK (multimodal pathology — TMA images, H&E slides, cell density) and MSK-CHORD (longitudinal genomics — genomic profiles, clinical timelines). Models act as agentic AI physicians, optionally using external tools (DrugBank, CONCH, PubMed). Each case contains multiple multi-choice questions; correctness is binary (matched vs. ground truth).